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The physician’s psychoactive medication resource guide
25% of your patients taking an antidepressant will have
weight gain and the weight gain is directly caused by the antidepressant.
If you are suffering from Sarafem side effects or Sarafem withdrawal side effects, there is an
answer and a solution.
The common Sarafem side effects of anxiety, insomnia, weight gain, or unwanted head feelings
can usually be handled quickly.
Whether you want to taper completely off Sarafem or just eliminate the existing side effects
caused by the medication, there is an answer and a solution.
Sarafem - Alert from the F.D.A.
FDA ALERT [07/2005]: Suicidal Thoughts or Actions in Children and Adults
Patients with depression or other mental illnesses often think about or attempt suicide. Closely
watch anyone taking antidepressants, especially early in treatment or when the dose is changed.
Patients who become irritable or anxious, or have new or increased thoughts of suicide or other
changes in mood or behavior (or their care givers) should contact their healthcare professional
Taking antidepressants may increase suicidal thoughts and actions in about 1 out of 50 people 18
years or younger. FDA has approved Zoloft for use in children only if they have obsessive-
Several recent scientific publications report the possibility of an increased risk for suicidal
behavior in adults who are being treated with antidepressant medications. Even before these
reports became available, FDA began a complete review of all available data to determine
whether there is an increased risk of suicidal thinking or behavior in adults being treated with
antidepressant medications. It is expected that this review will take a year or longer to complete.
In the meantime, FDA is highlighting that adults being treated with antidepressant medication,
particularly those being treated for depression, should be watched closely for worsening of
depression and for increased suicidal thinking or behavior.
This information reflects FDA’s preliminary analysis of data concerning this drug. FDA is
considering, but has not reached a final conclusion about, this information. FDA intends to update
this sheet when additional information or analyses become available.
Report medication side effects to the FDA. Click here (Opens New Browser)
PMDD is an unofficial "mental disorder." Unlike the recent Eli Lilly advertisements, a women must
experience five or more symptoms before the diagnosis can be made.
Eli Lilly is trying so hard to come up with another drug winner to replace Prozac in August 2001,
when their patent on Prozac expires, they are exhibiting obsessive-compulsive-disorder in their
PMDD symptoms are:
•Markedly depressed mood
•Decreased interest in activities
•Feeling sad, hopeless or self-deprecating
•Feeling tense, anxious or "on edge"
•Persistent irritability, anger and increased interpersonal conflicts
•Feeling fatigued, lethargic or lacking in energy
•Marked changes in appetite
•A subjective feeling of being overwhelmed or out of control
•Physical symptoms such as breast tenderness, swelling or bloating
New labeling for Sarafem ordered by the FDA
For Sarafem labeling -
Female Sexual Dysfunction with SSRIs—Although changes in sexual desire, sexual performance and sexual satisfaction often occur as
manifestations of a mood-related disorder, they may also be a consequence of pharmacologic treatment. In particular, some evidence
suggests that selective serotonin reuptake inhibitors (SSRIs) can cause such untoward sexual experiences. Reliable estimates of the
incidence and severity of untoward experiences involving sexual desire, performance, and satisfaction are difficult to obtain, however, in
part because patients and physicians may be reluctant to discuss them. Accordingly, estimates of the incidence of untoward sexual
experience and performance cited in product labeling, are likely to underestimate their actual incidence. For example, in women (age
18-45) receiving fluoxetine for indications other than PMDD, decreased libido was seen at an incidence of 4% for fluoxetine compared to
1% for placebo. There have been spontaneous reports in women (age 18-45) taking fluoxetine for indications other than PMDD of
orgasmic dysfunction, including anorgasmia.
Associated with Discontinuation in US Placebo-Controlled Clinical Trials (excluding data from extensions of trials) -
Text added at end of subsection -
Male and Female Sexual Dysfunction with SSRIs--Although changes in sexual desire, sexual performance, and sexual satisfaction often
occur as manifestations of a psychiatric disorder, they may also be a consequence of pharmacologic treatment. In particular, some
evidence suggests that SSRIs can cause such untoward sexual experiences. Reliable estimates of the incidence and severity of
untoward experiences involving sexual desire, performance, and satisfaction are difficult to obtain, however, in part because patients
and physicians may be reluctant to discuss them. Accordingly, estimates of the incidence of untoward sexual experience and
performance, cited in product labeling, are likely to underestimate their actual incidence. In patients enrolled in US depression, OCD,
and bulimia placebo-controlled clinical trials, decreased libido was the only sexual side effect reported by at least 2% of patients taking
fluoxetine (4% fluoxetine, < 1% placebo). There have been spontaneous reports in women taking fluoxetine of orgasmic dysfunction,
including anorgasmia. There are no adequate and well-controlled studies examining sexual dysfunction with fluoxetine treatment.
Priapism has been reported with all SSRIs.While it is difficult to know the precise risk of sexual dysfunction associated with the use of
SSRIs, physicians should routinely inquire about such possible side effects.